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From Cambridge University Press

Table 1: Typical costs and success rates for drug discovery

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Stage
Cost (M$)
Time (years)
Success rate (%)
Target Discovery
3.5
3
65
Screening
5
1
Medicinal chemistry
7
1
60
Pre-clinical development
6
1
50
Phase I clinical trial
10
Phase II clinical trial
10
5 over phases I, II, III
25 over phases I, II, III
Phase III clinical trial
140
Total
180
10
4

Notes:

Column 1: stage in drug discovery and development process.

Column 2: cost in US dollars.

Column 3: Time taken for this phase.

Column 4: typical success rate for that stage of the process for a project.

Source: Figures complied by Merlin from several pharmaceutical company sources, 1997-1999.


©2000 Fathom, Inc.